[an error occurred while processing this directive] [an error occurred while processing this directive]

Answer to your Health Question

Question (09/18/2012):

Title: Child getting repeated ITP problem.

Please help me to cure my child from getting repeated ITP problem.

I would be very grateful

Kunzang

Answer:

Dear Kunzang,

Thank you very much for your question.

You may find helpful information at:

What foods (items) should an ITP patient should avoid in her diet (those causes reduction of platelet count)?

Should herbal teas be used when you have ITP?

Low platelet count | ITP | Papaya leaf juice

Study published on September 6 , 2012 in The Journal of Thrombosis and Thrombolysis aimed to evaluate the efficacy, cost, and effects of anti-D immunoglobulin (anti-D Ig), methylprednisolone, or intravenous immunoglobulin (IVIG) therapy on the development of chronic disease in children who are Rh-positive with diagnosed immune thrombocytopenic purpura (ITP):

Children with newly diagnosed ITP and platelet count <20,000/mm(3) were prospectively randomized to treatment with anti-D Ig (50 ?g/kg), methylprednisolone (2 mg/kg/day), or IVIG (0.4 g/kg/day, 5 days).

Sixty children with a mean age of 6.7 years were divided into three equal groups. No difference was observed between platelet counts before treatment and on day 3 of treatment.

However, platelet counts at day 7 were lower in the methylprednisolone group than in the IVIG group (P = 0.03).

In the anti-D Ig group, hemoglobin and hematocrit levels were significantly lower at the end of treatment (P < 0.05).

Chronic ITP developed in 30 % of the anti-D Ig group, 35 % of the methylprednisolone group, and 25 % of the IVIG group, but no significant difference was noted among the groups.

The cost analysis revealed that the mean cost of IVIG was 7.4 times higher than anti-D Ig and 10.9 times higher than methylprednisolone.

In the treatment of ITP in childhood, one 50 ?g/kg dose of anti-D Ig has similar effects to IVIG and methylprednisolone.

Among patients who were treated with anti-D Ig, serious anemia was not observed, and the cost of treatment was less than that of IVIG treatment.


Do you have any other questions? Enter your health question

[an error occurred while processing this directive]