Interaction between B12 vitamin and Metoprolol, Ramipril and Bayer
been taking Metoprolol 25 mg and Ramipril 10 mg and Bayer 81 mg per
day for over 8 years.
now been told I have Anemia and need B12 supplements.
taking these medications cause malabsorption of B12 in my body?
you very much for your question.
is in a group of drugs called ACE inhibitors. ACE stands for
angiotensin converting enzyme.
inhibitors, have been associated with reduced absorption
or reduced serum levels of vitamin B12.
study of people hospitalized with heart disease, those who had been
taking aspirin were nearly twice as likely as nonusers to have
a low or marginally low blood level of vitamin B12.
Oijen MGH, Laheij RJF, Peters WHM, et al. Association of aspirin use
with vitamin B12 deficiency (results of the BACH study). The American
Journal of Cardiology 2004]
finding by itself does not prove that taking aspirin causes vitamin
B12 deficiency. However, aspirin is known to damage the stomach in
some cases, and the stomach plays a key role in vitamin B12 absorption
(by secreting hydrochloric acid and intrinsic factor).
is in a group of drugs called beta-blockers.
beta-adrenergic blockers (called "nonselective" beta blockers)
decrease the uptake of potassium from the blood into the cells.
RM, Silva P, Young JB, et al. Adrenergic modulation of extrarenal
potassium disposal. The New England Journal of Medicine 1980]
P. The effect of adrenergic blockade on potassium concentrations in
different conditions. Acta Medica Scandinavica 1983]
normalizes high blood pressure.
that have been associated with reduced absorption or reduced serum
levels of vitamin B12 include ACE inhibitors,
acetylsalicylic acid (aspirin), antibiotics, anticonvulsants,
bile acid sequestrants, colchicine, H2 blockers, metformin, neomycin,
nicotine, nitrous oxide, oral contraceptives, para-aminosalicylic
acid, potassium chloride, proton pump inhibitors (PPIs), and zidovudine
(AZT, Combivir®, Retrovir®).
you have any other questions? Enter
your health question