Lymph nodules showing up everywhere
I have a history of lymph nodules showing up anywhere and everywhere.
I had a 11mm lymph nodule on my liver it was there until early 2010.
it disappeared and one showed up a 7.6mm lymph nodule in the middle
lobe of my right lung and in Sept 2010 it disappeared.
of 2012, 3 lymph nodules one was a 4.2 another was a 2.2 and the third
was a 6.1 mm all inside my digestive system.
any diseases or conditions that fit my symptoms?
frequently at 1 or 2 times per month have lymph nodes behind my ears
and a line down both sides of the back of my neck under my chin like
where the salivary glands are and on the jaw bone right under the
front of each ear the all swell and hurt very bad.
within 4 days they star going away. Any help please
you very much for your question.
nodules are sites of lymphocyte (B-cells) proliferation/activation.
antibody production by B cells is implicated in many autoimmune diseases;
B cells are also susceptible to malignant transformation.
microbial antigens can activate B cells directly in the absence of
the source of damaging autoantibodies, have long been thought to depend
upon T cells for their activation.
scientists believed that B cells remain quiet in autoimmune diseases
unless they are stimulated first by T cells.
University researchers in 2008 proposed that once B cells are activated
via Toll-like receptors, they can subsequently recruit T cells and
that this can lead to a "vicious cycle" of chronic autoimmune
disease in which the two types of cell activate each other.
might explain why treatments that target T cells in autoimmune diseases
have fared relatively poorly, while newer treatments aimed at B cells
have shown great promise.
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