[an error occurred while processing this directive] [an error occurred while processing this directive]

Answer to your Health Question

Question:

Does parapsoriasis lead to skin cancer?

Does it affect the fetus; is there any cure for this?

Anu

Answer:

Dear Anu,

Parapsoriasis can progress to coetaneous T-cell lymphoma (CTCL) skin cancer if left untreated or treated inadequately.

Parapsoriasis can last a few weeks to several years or even a lifetime.

Parapsoriasis can be managed conservatively, based on symptoms. Often, topical treatment is effective

* Small plaque parapsoriasis usually is asymptomatic. Treatment should be based on alleviation of symptoms associated with scaliness. Patients should be reassured of the benign self-limiting nature of the disease.

-o- Emollients may be sufficient to treat scaliness; however, a trial of midpotency topical steroids (class 3-5) may lead to greater clinical responsiveness.

-o- Phototherapy is effective in treating lesions that are widely scattered. Broad- or narrow-band UV-B can be effective and can lead to remission.9,10 More recalcitrant presentations can be treated with psoralen and long-wave ultraviolet radiation (PUVA).

-o- Annual follow-up is recommended. An increase in the number of lesions, an increase in the size of lesions, or the development of induration or epidermal atrophy should prompt a repeat biopsy to consider a diagnosis ofMF in evolution.

* Large plaque parapsoriasis should be treated because this may prevent progression to MF (CTCL).

-o- Therapy includes mid- to high-potency topical steroids (class 2-4), topical nitrogen mustard, and topical carmustine (BCNU).

-o- Phototherapy with either broad- or narrow-band UV-B or PUVA can be effective in inducing remission.

-o- Follow-up every 6 months is recommended. Increasing number of lesions, increase in lesion size, or the development of induration or epidermal atrophy should prompt a repeat biopsy to consider a diagnosis of MF in evolution.

Pregnancy appeared to have no impact on the course of parapsoriasis en plaque, and no adverse effect was noted on pregnancy. Further studies are needed to clarify the interplay between pregnancy and parapsoriasis en plaque.

The effect of parapsoriasis on pregnancy, is still unknown.

Triamcinolone (Aristocort), a midpotency steroid formulation used to treat Parapsoriasis has fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus.

Do you have any other questions? Enter your health question

[an error occurred while processing this directive]