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Answer to your Health Question

Question (07/16/2011):

Title: My blood platelet count is 30,000.

Height: 5 ft. 2".

No Fever but when I checked my blood platelet is 30,000

Is it because of low Vitamin B12?

Its count 93

How Much Quantity I should take papaya leaves?

Is it one spoon daily?

Advice me for increase of platelet

(Khali Patte ka hi rush lena he tandel nikaldena he?)

Haresh

Answer:

Dear Haresh,

You may find information related to your questions at:

We didn't find any scientific evidence that papaya leaves can increase platelet count.

Low Platelet

Blood is composed of several types of cells, one of these are platelets, cells that are useful for blood clotting.

Platelets are formed from cells called megakaryocytes, if they are affected the number of platelets they produce is also affected.

Thrombocytopenia is a decrease in platelet count.

Platelets clump together to plug the injured area and stop the bleeding when a blood vessel is damaged and it begins to lose blood.

If you do not have the sufficient number of platelets, the cap is not performed, and bleeding (or exit of blood) continues to have significant impact, you can even bleed to death.

Platelets also carry serotonin and tryptophan, two substances involved in sleep-wake cycles, appetite and mood.

The decrease in the number of platelets may be due to several reasons, either because there is a low production, or an increase in its decomposition into the bloodstream, spleen, or liver.

Among the causes of low production of these cells are diseases such as anemia, bone marrow cancer, bone marrow infections and other illnesses.

In the case of viral hepatitis, thrombocytopenia may develop for various reasons.

One theory is that the virus in the case of Hepatitis C directly affects the megakaryocyte, the affected liver cells decreases the number of platelet production and increases their destruction.

Another theory and the theory most studied in recent years is that some of the drugs used to treat Hepatitis B and C, as pegylated interferon, produce a decrease in platelet count.

Also, antibodies that are produced in the immune system can accidentally attack platelets (producing a condition called Immune thrombocytopenic purpura or ITP).

Studies have reported that acute immune thrombocytopenia often is associated with Hepatitis A, B and C.

A normal platelet count ranges between 150,000 and 400,000 platelets per cubic millimeter of blood.

In severe cases of thrombocytopenia, platelet counts may approach zero. In mild cases, the platelet count is between 100,000 and 150,000.

If the platelet count falls below 30,000, it will present a high risk of irreversible bleeding, and even cerebral hemorrhage.

Symptoms depend on the severity of thrombocytopenia, a person with a mild one thrombocytopenia may have no symptoms, in more severe cases frequent and intense nosebleeds may be present, also known as epistaxis.

There are medicines to treat thrombocytopenia mediating the immune system in the case of immune thrombocytopenia, to bring down the destruction of platelets; there are also drugs that help in the production of platelets.

For Patients with active bleeding and count of less than 30.000 platelets, guidelines for action include:

Administer 1 dose of immunoglobulins intravenous (IGIV) and new assessment at 24h:

If the active bleeding persists it should be added corticosteroids and / or a second dose of immunoglobulin intravenous (IGIV)

If the bleeding disappears a new assessment must done in the next 72 hours.

And if the problem is clinical and analytically overcome then pass observation, but if persists by below of 20,000 or new active bleeding appears then treatment with corticosteroids should be started.

Anti-D immunoglobulin treatment may be tested in the case of Rh + or corticosteroid bolus. In medicine, a bolus is the administration of a medication, to raise its concentration in blood to an effective level.

The patient who is refractory to previous treatment and persist with clinical important bleeding must be sent to a specialized hospital for review and assessment of third line treatments.


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