is a beta-adrenergic blocking agent (beta-blocker) and is used for
treating high blood pressure.
is a long-acting calcium channel blocker and is used to treat high
Beta blockade is superior to Calcium channel blockade regarding chronotropic
properties of the myocardium.
is a histamine H2-receptor antagonist that inhibits stomach acid production
and is used to treat ulcers and gastroesophageal reflux disease (GERD).
is a proton pump inhibitor and is used to treat gastroesophageal reflux
who are experiencing inadequate control of NAB (Nocturnal Acid Breakthrough)on
a twice daily PPI (proton pump inhibitor), the addition of an H2RA
(histamine H2-receptor antagonist) to twice daily PPI therapy may
be more cost effective than adding a third bedtime dose of a PPI.
a state of hypothyroidism (underactivity) to a normal state (euthyroid
state) with levothyroxine may decrease the actions of certain beta-blocking
drugs, [for example, metoprolol (Lopressor)]. It may be necessary,
therefore, to change the dose of beta-blocker.
taking a Beta Blocker, [for example, metoprolol (Lopressor)] and Simvastatin,
possible patient's adverse outcomes are:
Heart Rate Decreased
taking Simvastatin, Metoprolol Tartrate and Levothyroxine, possible
patient's adverse outcomes are:
Transient Ischaemic Attack
of low potassium in the body are the formation of a potentially fatal
state called as "Hypokalemia".
condition of this disease leads to:
= muscle weakness and myalgia
= disturbed heart rhythm
= more risk of hyponatremia with confusion and seizures
and symptoms of low potassium are usually mild and at times vague.
It is not unusual to have more than one symptom concerning the kidneys,
muscles, nerves, heart and gastrointestinal tract. Some of the common
= cramping in arm or leg muscles. This is sometimes severe enough
to make it impossible to move arms or legs, similar to paralysis
= abdominal cramping or bloating
= nausea or vomiting
= tingling or numbness
= passing large quantity of urine or a frequent sensation of thirst
= irregular psychological behavior like depression, psychosis, delirium,
confusion or seeing or hearing things (hallucinations)
= fainting due to low blood pressure
= abnormal heart rhythms (arrhythmias)
hypokalemia is not linked with any symptoms, but may cause:
weakness - inability to exert force with one's muscles to the expected
= myalgia or muscle pain
= disturbed heart rhythm including ectopy (disturbance of the electrical
conduction system of the heart where beats arise from the wrong part
of the heart muscle)
= serious arrhythmias (electrical activity of the heart is irregular
i.e. faster or slower than normal)
= greater risk of hyponatremia (an electrolyte disturbance in humans
when the sodium concentration in the plasma decreases below 135 mmol/L)
with confusion and seizures
starting Lopressor dosage for people with high blood pressure
(hypertension) is 100 mg once a day or 50 mg twice a day. After a
week or longer, your healthcare provider may increase or decrease
your dosage based on the blood pressure response and/or Lopressor
is not a "one-size-fits-all" medication, and there is no
"standard" levothyroxine dosage. People have varying
degrees of hypothyroidism and other thyroid problems (and varying
responses to the medication), and, as a result, the levothyroxine
dose must be individualized.
daily Simvastatin dose is 5 mg to 80 mg
subjects a single 75 mg dose of ranitidine significantly
reduced meal-stimulated intragastric acidity.
oral dose of esomeprazole at 510 mg/kg (about 103 times the human
dose on a body surface area basis), was lethal to rats.
dose of esomeprazole is:
esophagitis: 40 mg/day
GERD: 20 mg/day
H. pylori eradication: 40 mg/day
initial antihypertensive oral dose of Amlodipine besylate tablets
is 5 mg once daily with a maximum dose of 10 mg once daily.
amlodipine or adding amlodipine at 2.5 mg in hepatically
impaired patients is recommended.