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Good morning. My doctor prescribed me Vartalon K but reading prospect of this drug it seems to me that it has interactions with anticoagulants.

I am under treatment with warfarin and thinking to take only half the prescribed dosage, at least 8 days.

Thanks for the advice.



Dear Maurice,

The active ingredient of Vartalon K is glucosamine sulfate.

Like many arthritis treatments, glucosamine (even when used without chondroitin) may possibly have hematologic effects that could cause it to interact with warfarin.

However, the evidence is far from conclusive.

The Arthritis Foundation does not currently recommend the use of glucosamine. If glucosamine sulfate is taken, it could very well interact with anticoagulants such as warfarin or heparin and cause increased bleeding tendencies.

On the other hand, there are reputable sources that indicate no serious interaction between glucosamine and warfarin.

If you decide to try glucosamine, your physician should monitor your International Normalized Ratio (INR) to keep a close look at your prothrombin time.

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