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Answer to your Health Question


I need to know if vartalon duo is recommended for osteoarthritis.

How does it help and if there are any sides effects? How long this drug should be taken?



Dear Karen,

Vartalon duo is a natural supplement. Its main ingredients are glucosamine sulfate and chondroitin sulfate

Glucosamine sulfate can improve pain and movement in knees affected by osteoarthritis based on information offered by RxList, The Internet Drug Index for prescription drugs and medications.

The long-term use of non-prescription chondroitin sulfate products or compounds appears to slow the worsening and ease the symptoms of osteoarthritis of the knee,based on information offered by a European study, published in the February 6, 2009 issue of Arthritis & Rheumatism.

The study found that people who used chondroitins 4 and 6 sulfate (CS) over two years lost less joint spacethan those on a placebo.

The decrease of pain was most significant in the first year the participants took the drug.

Based on information offered by Johns Hopkins Medicine large scale, independent studies of glucosamine and/or chondroitin have not shown a definitive benefit for the treatment of painful knee osteoarthritis (OA) and the effect of retarding knee OA progression remains controversial.

Dosing considerations for Glucosamine Sulfate:

Osteoarthritis: 1500 mg once daily or 500 mg three times daily

There is some concern that glucosamine products might cause allergic reactions in people who are sensitive to shellfish.

Glucosamine sulfate seems to be safe for most people. It can cause some mild side effects including nausea, heartburn, diarrhea, and constipation.

Uncommon side effects are drowsiness, skin reactions, and headache.

Dosing considerations for Chondroitin Sulfate:

Doses of 200-400 milligrams by mouth twice to three times daily, or 800-1,200 milligrams once daily have been used in studies. Higher doses (up to 2,000 milligrams) appear to have similar efficacy. In the treatment of osteoarthritis, full effects may take several weeks to occur.

It is not clear what dose is optimal when used in combination with glucosamine or whether the combination is as effective as or more effective than either agent alone.

For osteoarthritis, 50-100 milligrams as a single daily injection or divided into two daily injections has been used. Medical supervision is recommended.

Chondroitin sulfate seems to be safe for most people. It can cause some mild stomach pain and nausea. Other side effects that have been reported are diarrhea, constipation, swollen eyelids, legswelling, hair loss, and irregular heartbeat.

Some chondroitin products contain excess amounts of manganese.

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