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Answer to your Health Question

Question (08/22/2012):

Title: Foreign body reaction to sutures .

I had abdominal surgery for the 1st time in Feb 20th.

The surgeon used vicryl to sew the two inner incisions.

After the staples were removed an area the size of a silver dollar opened up and became infected.

In July I had another surgery where the vicryl suture were removed and replaced by monofilament sutures.

Again foreign body reaction occurred so those sutures were removed and replaced by nonfilament sutures and I am still having foreign body reaction.

Is it possible that this reaction will happen with all sutures?

And what should I do to get it to heal.


Thank you for your question.

Surgical suture material is usually inert and nontoxic and causes minimal inflammation of tissue.

However, foreign body reactions to various suture types can lead to granuloma, abscess, or even sinus formation.

Tissue reactivity, infection and wound dehiscence rate may be influenced by patient-related factors, e.g., diabetes, overweight, malignoma.

Whenever a foreign object is implanted in living tissue, a cellular response occurs.

Sutures usually produce a mild response that varies in character with different materials.

In their in vitro study, Katz et al. investigated the capability of bacteria to adhere to various types of sutures to cause tissue reactions.

The results showed that bacterial adherence to braided silk sutures was five- to eight folds higher as compared to nylon to which the least numbers of bacteria adhered.

Stillman et al, regarding the advantages of staples over sutures in contaminated wounds, states that skin tapes should be the preferred method of skin-wound closure.

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