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Question: How can a person with blood group A have antibody-B present in his plasma even though the person has no earlier exposure to antigen B? Tony

Answer: Dear Tony,

According to the ABO blood type system, there are four different blood types:

- Group A (A antigents and B antibodies)
- Group B (B antigents and A antibodies)
- Group AB (both A and B antigents and no A or B antibodies)
- Group O (no A or B antigents and both A and B antibodies)

Your blood type is defined by your genes.

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